Reproducibility of T1 mapping 11-heart beat MOLLI Sequence

Abstract

Methods 15 healthy volunteers (31±5 years, 8 males) with no known medical conditions, on no medication, underwent CMR scans (Avanto, Siemens, 1.5T) on two separate attendances with an 11 heart beat MOLLI 5(3)3. Following frequency adjustment, native T1 maps were obtained twice on a basal and a mid-ventricular slice respectively. 15 mins following GBCA administration (0.1 mmol/kg, Gadobutrol, Bayer, Germany) both image planes were acquired again twice. Pixel-wise T1 maps were analyzed offline by 2 independent blinded operators. A Region Of Interest was manually drawn in the septum for myocardium and blood in native and post gad images as shown in fig 1.