Leishmania major protein disulfide isomerase as a drug target

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate

Jörg Martin, Thomas Langer, Raina Boteva et al. · Nature · 1991 · 858 citations

Protein Chemistry, Chaperonin-mediated Protein Folding, Protein Assembly +9

Reduction of disulfides by thioredoxin. Exceptional reactivity of insulin and suggested functions of thioredoxin in mechanism of hormone action.

Arne Holmgren · Journal of Biological Chemistry · 1979 · 325 citations · Full text

Mammalian Thioredoxin, Insulin Disulfides, Redox Biology +17

A combined proteomic and transcriptomic approach to the study of stage differentiation in <b><i>Leishmania infantum</i></b>

François McNicoll, Jolyne Drummelsmith, Michaela Müller-McNicoll et al. · PROTEOMICS · 2006 · 156 citations

Immunologic Determinants of Disease Evolution in Localized Cutaneous Leishmaniasis due to<i>Leishmania major</i>

Hechmi Louzir, Peter C. Melby, Afif Ben Salah et al. · The Journal of Infectious Diseases · 1998 · 132 citations · Full text

Enzymes of Parasite Thiol Metabolism as Drug Targets

R. Luise Krauth‐Siegel, Graham H. Coombs · Parasitology Today · 1999 · 116 citations

Cellular Enzymology, Biochemistry, Antiparasitic Agent +5