Tyramine oxidase

Abstract

THE properties of tyramine, p-hydroxyphenylethylamine, have hitherto been studied almost entirely from the physiological, rather than from the bio- chemical standpoint. Dale and Dixon [1909] have reported that its effects on injection are similar to those produced by adrenaline, though less well marked. It is known to be one of the products produced from protein by the action of certain bacteria in the intestine of the higher animals, and toxic conditions occur simultaneously with increased absorption of these products into the blood stream. Also, its chemical relationship to tyrosine, and to adrenaline and thyroxine, render of interest any contribution to our knowledge of its metabolism.