Randomized trial of recombinant platelet factor 4 versus protamine for the reversal of heparin anticoagulation in humans. - Concepedia

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Randomized trial of recombinant platelet factor 4 versus protamine for the reversal of heparin anticoagulation in humans.

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1996

Year

Gregory Dehmer, Richard A. Lange, David A. Tate, Mark J. Pirwitz, W Daniel, Melrose Fisher, Eric M. Bonnem

Abstract

At the dose used in this study, rPF4 was well tolerated and reversed the anticoagulant effect of heparin. These data support its continued evaluation as an alternative to protamine after cardiac surgery.