Acute promyelocytic leukemia with isochromosome 17q and cryptic PML-RARA successfully treated with all-trans retinoic acid and arsenic trioxide

The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

F Grignani, Pier Francesco Ferrucci, Ugo Testa et al. · Cell · 1993 · 610 citations

Life Sciences, Molecular Biology, Oncology +11

All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol

Martin S. Tallman · Blood · 2002 · 498 citations · Full text

Medicine, Hematology, Oncology +13

Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia

Elihu H. Estey, Guillermo Garcia‐Manero, Alessandra Ferrajoli et al. · Blood · 2005 · 382 citations · Full text

Medicine, Oncology, Pharmacology +13

Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group

Francesco Lo‐Coco, Giuseppe Avvisati, Marco Vignetti et al. · Blood · 2010 · 342 citations

Medicine, Oncology, Chemotherapy +9

All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4)

Harry Iland, Ken Bradstock, Shane G. Supple et al. · Blood · 2012 · 340 citations · Full text

Medicine, Hematology, Oncology +15