PubMed · 2007 · 11 citations · 5 references
Veterinary MedicineInfectious DiseasesPathologyHistopathologyMedical MicrobiologyOral HistopathologyGranulomatous InflammationMycobacterial DiagnosticsOral Mucosal LesionsTuberculosis DiagnosisChronic Oral UlcersChronic Tuberculosis LesionsEpithelioid GranulomaOral Ulcer EtiologySputum ExaminationSputum MicroscopyTuberculosis DiagnosticsTuberculous Granuloma
Tuberculosis is a chronic infectious disease that can affect any part of the body, including the mouth. An upsurge in the number of tuberculosis cases, with a strong association with HIV infection, has been noted. We present a case of tuberculosis that clinically resembles a malignant chronic ulcer in the retromolar trigone-an uncommon site of occurrence. Histologically, the case demonstrated an atypical epitheloid granuloma with reduced lymphocyte count. The diagnosis of tuberculosis was confirmed following sputum culture of M tuberculosis. Antitubercular therapy improved the patient's condition. Although rare, tuberculosis must be considered as a differential diagnosis in chronic ulcers in the oral region; and its association with HIV must not be overlooked.
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Charles L. Daley, Peter M. Small, Gisela Schecter et al. · New England Journal of Medicine · 1992 · 996 citations · Full text
Bahar Sezer, Mert Zeytinoğlu, ÜMIT TUNCAY et al. · The Journal of the American Dental Association · 2004 · 57 citations
D.P. Von Arx, Abdurrahman Husain · BDJ · 2001 · 47 citations · Full text