Publication | Closed Access
The Toxicity of Organic Chemicals to Treatment Processes
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1992
Year
EngineeringChemical PollutantChemical AgentChemical ContaminantDrug ResistanceEnvironmental ChemistryNarcotic ChemicalsChemical SafetyBioremediationToxicologyEnvironmental MicrobiologyToxicological AspectEcotoxicologyEnvironmental FateChemical PollutionOrganic ChemicalsPharmacologyEnvironmental OrganismsEnvironmental EngineeringIc50 ConcentrationMicrobiologyEnvironmental ToxicologyMedicineMicrobiological DegradationDrug Analysis
The IC50 concentration was determined for a common set of narcotic chemicals to three classes of environmental organisms - aerobic heterotrophs, methanogens and Nitrosomonas as well as to MicrotoxR. The toxicity was well modeled using the linear solvation energy relationship which incorporates molecular volume, polarity/polarizability, hydrogen bond donor acidity and hydrogen bond donor basicity. Chemical characteristics which contribute to a chemical's toxicity are discussed. The relative toxicity to these different classes of environmental microorganisms is discussed and the implications to biological treatment process stability are considered.