PubMed · 1976 · 44 citations · 0 references
MedicineClinical SciencesSurgeryCardiothoracic SurgeryGastroenterologyGeneral SurgeryEsophageal DiseasesEsophageal SurgeryGastric DiseasesGastroesophageal Reflux DiseaseGastrointestinal SurgeryPeptic Ulcer DiseaseEtiologic HypothesisGastric PathologyGastric Ulcer DiseaseGastroesophageal Reflux PathophysiologyHiatal Hernia RepairPeptic EsophagitisPeptic Ulcer PathophysiologyReflux Esophagitis
Of 160 patients who underwent Nissen fundoplication for treatment of symptomatic peptic reflux esophagitis, five patients (3.1%) developed gastric ulcers. Four of these five patients experienced the "gas-bloat" syndrome. All ulcers were located on the lesser curvature of the stomach. Analyses of our experience with use of various types of hiatal hernia repair suggests that creation of the valvuloplastic mechanism unique to the Nissen procedure may be of etiologic significance in the development of gastric ulcers following this procedure.