Correlation of multimodality imaging in Paget's disease of bone.

Abstract

Paget's disease is asymptomatic in the majority of affected individuals, and may be discovered incidentally with diagnosis being made on routine radiographs obtained for other purposes. Sometimes the x-ray features are so typical that the diagnosis is straightforward. Bone scan should be the imaging technique of choice, because tracer uptake is directly related to degree of activity of disease, and it may advance any radiographic evidence. Vertebral involvement is better evaluated by CT. Both CT and MRI are recommended in spine complications (pathological fractures, radicular or cord compression syndromes, malignant degeneration).