The Journal of Urology · 1990 · 170 citations · 20 references
MedicineSurgeryAnesthesiaUrologic TraumaVascular SurgeryTraumatic Vascular InjuryVascular TraumaCavernosal InjuryIntracavernosal Injection TherapyPerineal Arteries
Two forms of priapism are known to occur. The more common type, veno-occlusive priapism, presents with a prolonged painful erection, and it is characterized by ischemia and pooling of blood within the corpora cavernosa. The less common form, high flow priapism, is characterized by lack of pain and ischemia. The pathophysiology of this disorder is poorly understood and the treatment is unclear. We report 2 cases of nonischemic priapism, one of which occurred after blunt perineal trauma and the other after intracavernosal self-injection with papaverine and phentolamine. Based on our 2 cases as well as a review of the literature (5 cases), we propose that the pathophysiological mechanism of this disorder is unregulated arterial inflow into the corpora, classify it as arterial priapism, and describe a diagnostic and therapeutic algorithm for its management.
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Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells
John A. Frangos, Suzanne G. Eskin, Larry V. McIntire et al. · Science · 1985 · 1.2K citations
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Tom F. Lue, Takao Takamura, Richard A. Schmidt et al. · The Journal of Urology · 1983 · 293 citations
Medicine, Anatomy, Physiology +11