Concepedia

Publication | Closed Access

Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa.

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Citations

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References

2008

Year

Łukasz Krakowczyk, Joanna Katarzyna Strzelczyk, Brygida Adamek, Marzena Zalewska−Ziob, Jerzy Arendt, Stanisław Półtorak, B. Maciejewski, Andrzej Wiczkowski
PubMed

Abstract

The older age and female gender are generally associated with higher methylation levels for most CpG islands in normal colonic mucosa. These results indicate that MGMT and/or p16 aberrant methylation may play an important role in colorectal cancer.