Colon cancer connections. Cancer syndrome meets molecular biology meets histopathology.

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

Life Sciences, Genetics, Oncology +14

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Medicine, Genetics, Molecular Genetics +17

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Fredrick S. Leach, Nicholas C. Nicolaides, Nickolas Papadopoulos et al. · Cell · 1993 · 2.3K citations

Life Sciences, Genetics, Molecular Genetics +17

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

Hans F. A. Vasen, Jukka‐Pekka Mecklin, P. Meera Khan et al. · Diseases of the Colon & Rectum · 1991 · 2.2K citations

Medicine, Genetics, Oncology +17

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +12