The Medical Journal of Australia · 1962 · 35 citations · 2 references
MedicineNephrologyPharmacotherapyClinical PharmacologyRenal PathophysiologyRenal PharmacotherapyChronic Kidney DiseaseRenal DiseaseRenal ImpairmentRenal PharmacologyChronic Organ FailureChronic Renal InsufficiencyImpaired Kidney FunctionRenal Drug SafetyRenal Failure ManagementRenal Function Evaluation
Deterioration in renal function has been observed in four patients who were taking co-trimoxazole. Three patients had stable chronic renal failure, and in two of these there was a further permanent impairment of renal function. The remaining patient received co-trimoxazole while recovering from a short episode of acute oliguric renal failure. It is suggested that co-trimoxazole be withheld, or used with caution in patients with impaired renal function.
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