Blockade of nitric oxide formation by mitigates ischemic brain edema and subsequent cerebral infarction in rats

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

Joseph S. Beckman, ThomasJ Beckman, Jake Y. Chen et al. · Proceedings of the National Academy of Sciences · 1990 · 7.1K citations

Life Sciences, Biochemistry, Cell Biology +15

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

David S. Bredt, Solomon H. Snyder · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Biochemistry, Cell Biology +13

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

David S. Bredt, Paul M. Hwang, Charles E. Glatt et al. · Nature · 1991 · 2.4K citations

Life Sciences, Biochemistry, Molecular Biology +9

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

Valina L. Dawson, Ted M. Dawson, Edythe D. London et al. · Proceedings of the National Academy of Sciences · 1991 · 2.2K citations

Life Sciences, Neurobiology, Neuroscience +17

Neuronal NADPH diaphorase is a nitric oxide synthase.

Bruce T. Hope, G J Michael, Karl M. Knigge et al. · Proceedings of the National Academy of Sciences · 1991 · 1.9K citations

Life Sciences, Neurobiology, Neuroscience +13