Extra-medullary hematopoiesis causing bilateral optic atrophy in beta thalassemia/Hb E disease.

Abstract

Extra-medullary hematopoiesis in beta thalassemia can involve paranasal sinuses and cause compressive neuropathy. In patients with beta thalassemia that required multiple blood transfusions with progressive visual loss, ectopic marrow compression of optic nerve should be ruled out.