DIABETIC ACIDOSIS: AN EVALUATION OF THE CAUSE, COURSE AND THERAPY OF 73 CASES

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Article1 January 1960DIABETIC ACIDOSIS: AN EVALUATION OF THE CAUSE, COURSE AND THERAPY OF 73 CASESALAN S. COHEN, M.D., VERNON K. VANCE, M.D., JOHN W. RUNYAN JR., M.D., F.A.C.P., DAVID HURWITZ, M.D.ALAN S. COHEN, M.D.Search for more papers by this author, VERNON K. VANCE, M.D.Search for more papers by this author, JOHN W. RUNYAN JR., M.D., F.A.C.P.Search for more papers by this author, DAVID HURWITZ, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-52-1-55 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONDiabetic acidosis until recently ranked high among the causes of death in any series of diabetic patients. The fall in mortality in the last few years has been clearly documented by Root.1 However, the case fatality rate in this complication of diabetes mellitus is still quite significant, and in a relatively recent publication has been noted to vary from 2.4% to 43.7% at a group of large general hospitals.2Among the many factors contributing to the lowering of mortality are the early and adequate use of insulin, the advent of antibiotic therapy for associated and complicating infections, and the...Bibliography1. Root HF: Treatment of diabetic coma, J. Chron. Dis. 2: 121, 1955. CrossrefMedlineGoogle Scholar2. Harwood R: Diabetic acidosis. Results of treatment in 67 consecutive cases, New England J. Med. 245: 1, 1951. CrossrefMedlineGoogle Scholar3. Butler AM: Parenteral fluid therapy in diabetic coma, Acta paediat. 38: 59, 1949. CrossrefGoogle Scholar4. Butler AM: Diabetic coma, New England J. Med. 243: 648, 1950. CrossrefMedlineGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication March 7, 1959.From the Thorndike Memorial Laboratory and the Second and Fourth (Harvard) Medical Services, Boston City Hospital, the Department of Medicine, Harvard Medical School, and the Diabetes Service, Boston City Hospital. These studies were aided by USPHS Training Grant #2A-5060.Requests for reprints should be addressed to Alan S. Cohen, M.D., Department of Medicine, Arthritis Unit, Massachusetts General Hospital, Boston 14, Massachusetts. 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LEHRNER, M.D., Ph.D., ROBERT C. KARN, Ph.D., A. DONALD MERRITT, M.D.7 Brittle diabetesComa diabeticumDiabetes und Stress-Situationen (Operationen, Infektionen, sonstige Stress-Situationen)Pathogenesis, diagnosis and treatment of diabetic ketoacidosisINTENSIVE CARE IN THE MANAGEMENT OF DIABETIC KETOACIDOSISThiazides and hypokalaemia in diabetic ketoacidosisDANGERS OF INTRAVENOUS FRUCTOSERegulation of ketogenesis and clinical aspects of the ketotic stateReferences 1 January 1960Volume 52, Issue 1Page: 55-86KeywordsDiabetes mellitusEmotionsFallsHospital medicineInsulinInsulin-like growth factorsMedical servicesMortalityResearch laboratoriesWalking ePublished: 1 December 2008 Issue Published: 1 January 1960 PDF downloadLoading ...