Concepedia

World Health Organization and International League of Associations for Rheumatology core endpoints for symptom modifying antirheumatic drugs in rheumatoid arthritis clinical trials.

Maarten Boers, Peter Tugwell, Felson Dt, van Riel Pl, John Kirwan, Edmonds Jp, Smolen Js, N. Khaltaev, Muirden Kd

PubMed · 1994 · 308 citations · 15 references

Concepts

Abstract

The WHO/ILAR core set of endpoints for rheumatoid arthritis clinical trials signifies progress in a continuing worldwide effort. This core set includes the following measures: pain, patient global assessment, physical disability, swollen joints, tender joints, acute phase reactants, and physician global assessment; in studies of one or more years' duration, radiographs of joints should be performed.

References

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Which traditional measures should be used in rheumatoid arthritis clinical trials?

Jennifer J. Anderson, David T. Felson, Robert F. Meenan et al. · Arthritis & Rheumatism · 1989 · 139 citations

, , +15