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Carbamazepine-Induced Liver Injury
28
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1983
Year
HepatologyCarbamazepine-induced Liver InjuryMedicineLiver PhysiologyIdiosyncratic Hypersensitivity TypeHepatitisPathologyPrompt RecoveryHepatotoxicityPharmacotherapyLiver DiseaseHepatology FibrosisPharmacologyDrug-induced Liver InjuryCirrhosis
Two patients had carbamazepine-induced liver injury. The clinical, biochemical, and histologic data suggest hepatitis of the idiosyncratic hypersensitivity type with granulomas in one patient; in the other, the liver injury resembles that caused by a hepatotoxin. Both patients showed prompt recovery upon discontinuation of the drug.