Feasibility of Developing a Neural Network for Prediction of Human Pharmacokinetic Parameters from Animal Data

Interspecies scaling, allometry, physiological time, and the ground plan of pharmacokinetics

Harold Boxenbaum · Journal of Pharmacokinetics and Biopharmaceutics · 1982 · 640 citations

Pharmacokinetic Modeling, Pharmacological Study, Medicine +8

Neural networks: A new method for solving chemical problems or just a passing phase?

Jure Zupan, Johann Gasteiger · Analytica Chimica Acta · 1991 · 581 citations

Evolving Neural Network, Engineering, Chemical Problems +11

Man versus Beast: Pharmacokinetic Scaling in Mammals

Joyce Mordenti · Journal of Pharmaceutical Sciences · 1986 · 389 citations

Animal Physiology, Pharmacological Study, Medicine +4

Interspecies correlation of plasma concentration history of methotrexate (NSC-740).

Robert L. Dedrick, Kenneth B. Bischoff, Daniel S. Zaharko · PubMed · 1970 · 185 citations

Medicine, Pharmacology, Analytical Chemistry +6

Interspecies Comparison of In Vivo Caffeine Pharmacokinetics in Man, Monkey, Rabbit, Rat and Mouse

Maurizio Bonati, Roberto Latini, Gianni Tognoni et al. · Drug Metabolism Reviews · 1984 · 170 citations

Pharmacokinetic Modeling, Pharmacological Study, Medicine +11