Concepedia

Signal transduction and downregulation of C-MET in HGF stimulated low and highly metastatic human osteosarcoma cells

Knut Husmann, Pascal Ducommun, Adam A. Sabile, Else‐Marie Pedersen, Walter Born, Bruno Fuchs

Biochemical and Biophysical Research Communications · 2015 · 11 citations · 20 references

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20

Molecular cloning of a new transforming gene from a chemically transformed human cell line

Colin S. Cooper, Morag Park, Donald G. Blair et al. · Nature · 1984 · 991 citations

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Functional Expression and Mutations of c-Met and Its Therapeutic Inhibition with SU11274 and Small Interfering RNA in Non–Small Cell Lung Cancer

C. Patrick, Ramasamy Jagadeeswaran, Simha Jagadeesh et al. · Cancer Research · 2005 · 578 citations

, , +14

Enhanced Tumorigenicity and Invasion-Metastasis by Hepatocyte Growth Factor/Scatter Factor-Met Signalling in Human Cells Concomitant with Induction of the Urokinase Proteolysis Network

Michael Jeffers, Sing Rong, George F. Vande Woude · Molecular and Cellular Biology · 1996 · 313 citations · Full text

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The Met/HGF receptor is over-expressed in human osteosarcomas and is activated by either a paracrine or an autocrine circuit.

Riccardo Ferracini, Maria Flavia Di Renzo, Katia Scotlandi et al. · PubMed · 1995 · 284 citations

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BindingDB Entry 50022503: A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.

PubMed · 2025 · 236 citations · Full text

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