Concepedia

Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis

Jin Chai, Shi‐Ying Cai, Xiaocong Liu, Wei Lian, Sheng Chen, Liangjun Zhang, Xinchan Feng, Ying Cheng, Xiaochong He, Yu He,

Journal of Hepatology · 2015 · 64 citations · 31 references

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31

Recognition of the polyubiquitin proteolytic signal

Julia S. Thrower, Laura Hoffman, Martin Rechsteiner et al. · The EMBO Journal · 2000 · 1.7K citations · Full text

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Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

Coen C. Paulusma, Piter J. Bosma, Guido J.R. Zaman et al. · Science · 1996 · 832 citations

, , +17

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

Michael Trauner, Marco Arrese, CJ Soroka et al. · Gastroenterology · 1997 · 499 citations

, , +17

Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes

Shojiro Kikuchi, Masaki Hata, Kanehisa Fukumoto et al. · Nature Genetics · 2002 · 308 citations

, , +13

Ezrin is a downstream effector of trafficking PKC–integrin complexes involved in the control of cell motility

Tony Ng · The EMBO Journal · 2001 · 296 citations · Full text

, , +16