PubMed · 1985 · 106 citations · 0 references
PharmacyPharmacologyPharmacotherapyCardiovascular PharmacotherapyClinical PharmacologyPharmaceutical ComplianceBlood Pressure ControlBlood Pressure ManagementHypertension ControlHypertension ManagementMedication AdherencePatient AdherenceAdherence MeasurementAdherence To Antihypertensive TherapyAntihypertensive Drug TherapyAntihypertensive Medication AdherenceBlood PressureBlood Pressure MeasurementComplianceDrug Combination Therapy
Compliance with antihypertensive therapy was measured before and after distribution of non-automatic blood pressure devices. After 2 weeks of placebo treatment, 37 patients were treated with an antihypertensive combination drug containing triamterene. Adherence to therapy was assessed over 8 months by measuring urine fluorescence due to triamterene at intervals of 2-4 weeks, unknown to the patients. After 3 months of therapy, all patients, not just those with poor compliance, were given blood pressure devices and were carefully instructed in their use. The results showed that self-recording of blood pressure increased the compliance rate in the total group from 65% at the beginning of the study to 81% at the end. In those who initially showed poor compliance, there was an increase in compliance from 0 to 70% after self-measuring of blood pressure was introduced. We conclude that self-recording of blood pressure may be of value in patients with unsatisfactory blood pressure responses in whom poor compliance is suspected.