Upregulation of NMDA Receptors in Hippocampus and Cortex in the Pentylenetetrazol-Induced “Kindling” Model of Epilepsy

A permanent change in brain function resulting from daily electrical stimulation

Graham V. Goddard, Dan McIntyre, Curtis K. Leech · Experimental Neurology · 1969 · 3.1K citations

Stimulation Device, Deep Brain Stimulation, Neuromodulation +15

The role of glutamate in epilepsy and other CNS disorders.

Brian S. Meldrum · PubMed · 1994 · 478 citations

Synaptic Transmission, Neurotransmitter, Neurotransmission +18

Ligand affinities at recombinant receptors depend on subunit composition

David Laurie, P. H. Seeburg · European Journal of Pharmacology Molecular Pharmacology · 1994 · 381 citations

Signal Transduction, Functional Selectivity, G Protein-coupled Receptor +3

The kindling model of epilepsy: a critical review.

James O McNamara, Douglas W. Bonhaus, Chul-Jin Shin et al. · PubMed · 1985 · 185 citations

Kindling Studies, Critical Review, Brain Mechanism +17

Properties of NMDA receptor channels in neurons acutely isolated from epileptic (kindled) rats

Georg Köhr, Yves De Koninck, István Módy · Journal of Neuroscience · 1993 · 167 citations · Full text

Synaptic Transmission, Neurotransmitter, Neurotransmission +18