The JAX Cancer Center

Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis

Peishan Li, Ming Lü, Jiayuan Shi et al. · Nature Immunology · 2020 · 242 citations · Full text

Medicine, Cell Biology, Oncology +12

Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

Devon S. Svoboda, M. Inmaculada Barrasa, Jian Shu et al. · Proceedings of the National Academy of Sciences · 2019 · 222 citations · Full text

Medicine, Neurobiology, Neuroscience +17

CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence

Yue Zhao, Ziwei Pan, Sandeep Namburi et al. · EBioMedicine · 2020 · 135 citations · Full text

Life Sciences, Bioinformatics, Oncology +17

CRISPR artificial splicing factors

Menghan Du, Nathaniel Jillette, Jacqueline Jufen Zhu et al. · Nature Communications · 2020 · 122 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing

Sara Parsa, Ana Ortega-Molina, Hsia‐Yuan Ying et al. · Nature Cancer · 2020 · 71 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16