Novalex Therapeutics (United States)

Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus

Hyun Lee, Jinhong Ren, Salvatore Nocadello et al. · Antiviral Research · 2016 · 131 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +14

Benzimidazole-Based FabI Inhibitors: A Promising Novel Scaffold for Anti-staphylococcal Drug Development

Tina L. Mistry, Lena Truong, Arun K. Ghosh et al. · ACS Infectious Diseases · 2016 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI)

Shahila Mehboob, Jinhua Song, Kirk E. Hevener et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

A novel series of enoyl reductase inhibitors targeting the ESKAPE pathogens, Staphylococcus aureus and Acinetobacter baumannii

Ji-Eun Kwon, Tina L. Mistry, Jinhong Ren et al. · Bioorganic & Medicinal Chemistry · 2017 · 20 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Determination of absolute configuration and binding efficacy of benzimidazole-based FabI inhibitors through the support of electronic circular dichroism and MM-GBSA techniques

Jinhong Ren, Tina L. Mistry, Pin‐Chih Su et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 10 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Discovery +14