Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

Aaron D. Goldberg, Laura A. Banaszynski, Kyung‐Min Noh, +26

Cell

Histone ModificationsChromatinChromatin StructureChromatin RemodelingNatural Sciences +12

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Elena Pérez, Jianbin Wang, Jeffrey C. Miller, +20

Nature Biotechnology

Viral ReplicationHiv-1 ResistanceNatural SciencesHuman RetrovirusImmunology +10

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

Vipula K. Shukla, Yannick Doyon, Jeffrey C. Miller, +22

Nature

BiologyPrecise Genome ModificationPlant GeneticsGeneticsZinc-finger Nucleases +7

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Keith D. Robertson, Slimane Ait‐Si‐Ali, Tomoki Yokochi, +3

Nature Genetics

ChromatinTranscriptional RegulationMedicineGeneticsNatural Sciences +9

Histone Deimination Antagonizes Arginine Methylation

Graeme L. Cuthbert, Sylvain Daujat, Andrew Snowden, +8

Cell

Histone ModificationsChromatinChromatin RemodelingNatural SciencesEpigenetic Change +8

In vivo genome editing restores haemostasis in a mouse model of haemophilia

Hojun Li, Virginia Haurigot, Yannick Doyon, +17

Nature

Vivo GenomeKnockout MouseEngineeringGenome SurgeryGenetics +10

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

Chandrasekhar Kanduri, Vinod Pant, Dmitri Loukinov, +5

Current Biology

ChromatinH19 GeneChromatin StructureNatural SciencesGenetics +13

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

Russell C. DeKelver, Vivian M. Choi, Erica A. Moehle, +24

Genome Research

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction

Laurie H. Sanders, Josée Laganière, Oliver Cooper, +13

Neurobiology of Disease

MitophagyNeurodegenerative DiseasesMolecular NeuroscienceMitochondrial FunctionGenetics +9

Gene-Specific Targeting of H3K9 Methylation Is Sufficient for Initiating Repression In Vivo

Andrew Snowden, Philip D. Gregory, Casey C. Case, +1

Current Biology

Histone ModificationsChromatinTranscriptional RegulationGene-specific TargetingEpigenetic Change +10