Parion Sciences (United States)

Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice

Laura A. Hancock, Corinne E. Hennessy, George M. Solomon et al. · Nature Communications · 2018 · 230 citations · Full text

Mechanosensitive ATP Release Maintains Proper Mucus Hydration of Airways

Brian Button, Seiko F. Okada, C. Brandon Frederick et al. · Science Signaling · 2013 · 116 citations · Full text

An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases

Camille Ehré, Zachary L. Rushton, Boya Wang et al. · American Journal of Respiratory and Critical Care Medicine · 2018 · 115 citations

Evaluation of Second Generation Amiloride Analogs as Therapy for Cystic Fibrosis Lung Disease

Andrew J. Hirsh, Juan Sabater, Andra Zamurs et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 94 citations

Long term effects of denufosol tetrasodium in patients with cystic fibrosis

Félix Ratjen, Todd A. Durham, Tomáš Navrátil et al. · Journal of Cystic Fibrosis · 2012 · 93 citations · Full text

Pathology, Long Term Effects, Pulmonary Fibrosis +2