Stabilité génétique et oncogenèse

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

Clélia Coutzac, Jean-Mehdi Jouniaux, Angélo Paci et al. · Nature Communications · 2020 · 441 citations · Full text

SAMHD1 acts at stalled replication forks to prevent interferon induction

Flavie Coquel, Maria João Silva, Hervé Técher et al. · Nature · 2018 · 433 citations

Natural Sciences, Genetics, Stalled Replication Forks +4

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

Slimane Ait‐Si‐Ali, François‐Xavier Barre, Fatima Dkhissi et al. · Nature · 1998 · 302 citations

Histone Modifications, Chromatin, Histone Acetyltransferase Activity +12

BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells.

Florence Le Page, Voahangy Randrianarison, Didier Marot et al. · PubMed · 2000 · 192 citations

Molecular Biology, Transcription-coupled Repair, Redox Biology +16

A stemness-related ZEB1–MSRB3 axis governs cellular pliancy and breast cancer genome stability

Anne‐Pierre Morel, Christophe Ginestier, Roxane M. Pommier et al. · Nature Medicine · 2017 · 177 citations

Cancer Research, Cell Regulation, Medicine +8