AB2 Bio (Switzerland)

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome

Eric S. Weiss, Charlotte Girard, Dirk Holzinger et al. · Blood · 2018 · 395 citations · Full text

Life Sciences, Immunology, Pathology +12

Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's disease

Cem Gabay, Bruno Fautrel, Jürgen Rech et al. · Annals of the Rheumatic Diseases · 2018 · 291 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17

Elevated serum levels of free interleukin-18 in adult-onset Still’s disease

Charlotte Girard, Jürgen Rech, Michael Brown et al. · Lara D. Veeken · 2016 · 170 citations

Life Sciences, Immunology, Autoimmunity +12

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

Qiqun Zeng, Sadegh Saghafinia, Agnieszka Chryplewicz et al. · Science · 2022 · 86 citations · Full text

Medicine, Immunology, Oncology +17

IL-18 as therapeutic target in a patient with resistant systemic juvenile idiopathic arthritis and recurrent macrophage activation syndrome

Shima Yasin, Krista Solomon, Scott Canna et al. · Lara D. Veeken · 2019 · 80 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17