Concepedia

Proteus (United Kingdom)

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Publications

67

Citations

14.6K

Authors

9

Location

Belfast, United Kingdom

Proteus (United Kingdom) is a company institution in Belfast, United Kingdom known for pharmacy, medicinal chemistry, and drug design.

Top concepts

Drug DesignMedicinal ChemistryLigand BindingProtein-ligand DockingChemistryComputational ChemistryStructural BiologyLife SciencesPharmacyChemical Space Exploration

Publications

67

Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes

Matthew Eldridge, Christopher W. Murray, T.R. Auton et al. · Journal of Computer-Aided Molecular Design · 1997 · 1.7K citations

Pharmacy, Bioinformatics, Medicinal Chemistry +12

A Mosaic Activating Mutation in <i>AKT1</i> Associated with the Proteus Syndrome

Marjorie J. Lindhurst, Julie C. Sapp, Jamie K. Teer et al. · New England Journal of Medicine · 2011 · 887 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Flexible docking using tabu search and an empirical estimate of binding affinity

Carol A. Baxter, Christopher W. Murray, David E. Clark et al. · Proteins Structure Function and Bioinformatics · 1998 · 367 citations

Life Sciences, Chemistry, Computational Chemistry +16

The sensitivity of the results of molecular docking to induced fit effects: Application to thrombin, thermolysin and neuraminidase

Christopher W. Murray, Carol A. Baxter, A. David Frenkel · Journal of Computer-Aided Molecular Design · 1999 · 160 citations

Life Sciences, Molecular Biology, Biomolecular Modeling +10

Empirical scoring functions. II. The testing of an empirical scoring function for the prediction of ligand-receptor binding affinities and the use of Bayesian regression to improve the quality of the model

Christopher W. Murray, T.R. Auton, Matthew Eldridge · Journal of Computer-Aided Molecular Design · 1998 · 137 citations

Pharmacy, Biostatistics, Medicinal Chemistry +16

1–5 of 67

Authors

9

1–5 of 9