Zymenex (Denmark)

Enzyme replacement improves nervous system pathology and function in a mouse model for metachromatic leukodystrophy

Ulrich Matzner, Eva Herbst, Kerstin Khalaj Hedayati et al. · Human Molecular Genetics · 2005 · 148 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Reversal of peripheral and central neural storage and ataxia after recombinant enzyme replacement therapy in α-mannosidosis mice

Judith Blanz, Stijn Stroobants, Renate Lüllmann‐Rauch et al. · Human Molecular Genetics · 2008 · 67 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Variations in Porphobilinogen and 5-Aminolevulinic Acid Concentrations in Plasma and Urine from Asymptomatic Carriers of the Acute Intermittent Porphyria Gene with Increased Porphyrin Precursor Excretion

Ylva Flodérus, Eliane Sardh, Christer Möller et al. · Clinical Chemistry · 2006 · 67 citations · Full text

Life Sciences, Biochemistry, Excretion +15

Enzyme Replacement Improves Ataxic Gait and Central Nervous System Histopathology in a Mouse Model of Metachromatic Leukodystrophy

Ulrich Matzner, Renate Lüllmann‐Rauch, Stijn Stroobants et al. · Molecular Therapy · 2009 · 66 citations · Full text

Life Sciences, Neurology, Pharmacology +17

Efficacy and safety of Velmanase alfa in the treatment of patients with alpha‐mannosidosis: results from the core and extension phase analysis of a phase III multicentre, double‐blind, randomised, placebo‐controlled trial

Line Borgwardt, Nathalie Guffon, Yasmina Amraoui et al. · Journal of Inherited Metabolic Disease · 2018 · 62 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +7