Windtree Therapeutics (United States)

Treatment with 24 Hour Istaroxime Infusion in Patients Hospitalised for Acute Heart Failure: A Randomised, Placebo-Controlled Trial

Valentina Carubelli, Yuhui Zhang, Marco Metra et al. · European Journal of Heart Failure · 2020 · 62 citations

SERCA2a stimulation by istaroxime improves intracellular Ca2+ handling and diastolic dysfunction in a model of diabetic cardiomyopathy

Eleonora Torre, Martina Arici, Alessandra Maria Lodrini et al. · Cardiovascular Research · 2021 · 50 citations · Full text

Safety and efficacy of istaroxime in patients with acute heart failure‐related pre‐cardiogenic shock – a multicentre, randomized, double‐blind, placebo‐controlled, parallel group study ( <scp>SEISMiC</scp> )

Marco Metra, Ovidiu Chioncel, Gad Cotter et al. · European Journal of Heart Failure · 2022 · 39 citations · Full text

Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure

Andrea Luraghi, Mara Ferrandi, Paolo Barassi et al. · Journal of Medicinal Chemistry · 2022 · 25 citations · Full text

Antihypertensive treatment guided by genetics: PEARL-HT, the randomized proof-of-concept trial comparing rostafuroxin with losartan

Lorena Citterio, Giuseppe Bianchi, Giuseppe Scioli et al. · The Pharmacogenomics Journal · 2021 · 24 citations · Full text