UCB Pharma (Japan)

The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression

Tatsuya Atsumi, Kazuhiko Yamamoto, Tsutomu Takeuchi et al. · Annals of the Rheumatic Diseases · 2015 · 109 citations · Full text

Separation of Antiepileptogenic and Antiseizure Effects of Levetiracetam in the Spontaneously Epileptic Rat (SER)

Hai Yan, Jiqun Cai, Kumatoshi Ishihara et al. · Epilepsia · 2005 · 83 citations · Full text

Efficacy and safety of certolizumab pegol plus methotrexate in Japanese rheumatoid arthritis patients with an inadequate response to methotrexate: the J-RAPID randomized, placebo-controlled trial

Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka et al. · Modern Rheumatology · 2013 · 63 citations · Full text

Efficacy and safety of olokizumab in Asian patients with moderate-to-severe rheumatoid arthritis, previously exposed to anti-TNF therapy: Results from a randomized phase II trial

Tsutomu Takeuchi, Yoshiya Tanaka, Hisashi Yamanaka et al. · Modern Rheumatology · 2015 · 57 citations · Full text

Efficacy and safety of certolizumab pegol without methotrexate co-administration in Japanese patients with active rheumatoid arthritis: The HIKARI randomized, placebo-controlled trial

Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka et al. · Modern Rheumatology · 2013 · 55 citations · Full text