NeuroVive Pharmaceutical (Sweden)

Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency

Johannes K. Ehinger, Sarah Piel, Rhonan Ford et al. · Nature Communications · 2016 · 151 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition

Sarah Piel, Johannes K. Ehinger, Eskil Elmér et al. · Acta Physiologica · 2014 · 69 citations

Life Sciences, Biochemistry, Pharmacology +17

Neuroprotective Effects of Cyclosporine in a Porcine Pre-Clinical Trial of Focal Traumatic Brain Injury

Michael Karlsson, Bryan Pukenas, Sanjeev Chawla et al. · Journal of Neurotrauma · 2018 · 41 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Copenhagen Head Injury Ciclosporin Study: A Phase IIa Safety, Pharmacokinetics, and Biomarker Study of Ciclosporin in Severe Traumatic Brain Injury Patients

Jesper Kelsen, Michael Karlsson, Magnus J. Hansson et al. · Journal of Neurotrauma · 2019 · 36 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production

Sarah Piel, Johannes K. Ehinger, Imen Chamkha et al. · Intensive Care Medicine Experimental · 2018 · 26 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17