MEI Pharma (United States)

Reinforced Adversarial Neural Computer for <i>de Novo</i> Molecular Design

Arip Asadulaev, Yan A. Ivanenkov, Vladimir Aladinskiy et al. · Journal of Chemical Information and Modeling · 2018 · 387 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +12

Adversarial Threshold Neural Computer for Molecular <i>de Novo</i> Design

Arip Asadulaev, Quentin Vanhaelen, Yan A. Ivanenkov et al. · Molecular Pharmaceutics · 2018 · 225 citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +14

Phase 2, randomized, double‐blind study of pracinostat in combination with azacitidine in patients with untreated, higher‐risk myelodysplastic syndromes

Guillermo Garcia‐Manero, Guillermo Montalban‐Bravo, Jesús G. Berdeja et al. · Cancer · 2017 · 105 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study

Guillermo Garcia‐Manero, Yasmin Abaza, Koichi Takahashi et al. · Blood Advances · 2019 · 86 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies

Yasmin Abaza, Tapan M. Kadia, Elias Jabbour et al. · Cancer · 2017 · 58 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16