Concepedia
Institution (Company)
Exicure (United States)
Also Known As
AuraSense Therapeutics, Exicure (United States)
47
Publications
4.5K
Citations
2
Authors
35
Concepts
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Multiplexed Nanoflares: mRNA Detection in Live Cells
Andrew E. Prigodich, Pratik S. Randeria, William E. Briley, +4
Analytical Chemistry
NanoparticlesNanomedicineEngineeringDistinct Mrna TargetsNanobiotechnology +12
2012
284
Immunomodulatory spherical nucleic acids
Aleksandar F. Radovic‐Moreno, Natalia Chernyak, Christopher C. Mader, +11
Proceedings of the National Academy of Sciences
2015
247
miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma
Fotini M. Kouri, Lisa Hurley, Weston L. Daniel, +15
Genes & Development
Mature Mir-182 DuplexesCancer BiologyGliomaTumor BiologyNeuro-oncology +16
220
Induction of Telomere Dysfunction Mediated by the Telomerase Substrate Precursor 6-Thio-2′-Deoxyguanosine
İlgen Mender, Sergei Gryaznov, Z. Günnur Dikmen, +2
Cancer Discovery
2014
157
Exosome Encased Spherical Nucleic Acid Gold Nanoparticle Conjugates as Potent MicroRNA Regulation Agents
Ali H. Alhasan, Pinal C. Patel, Chung Hang Jonathan Choi, +1
Small
2013
102
Targeting the IL-17 Receptor Using Liposomal Spherical Nucleic Acids as Topical Therapy for Psoriasis
Haoming Liu, Richard S. Kang, Katherine Bagnowski, +9
Journal of Investigative Dermatology
2019
55
Modeling of movement of liquid metal droplets driven by an electric field
M. F. Wang, Mingjiang Jin, Xuejun Jin, +1
Physical Chemistry Chemical Physics
2017
51
A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells
İlgen Mender, Sergei Gryaznov, Jerry W. Shay
Oncoscience
Genome InstabilityDrug TargetingMedicineCell InteractionPharmacology +12
38
A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation
Weston L. Daniel, Ulrike Lorch, Scott Mix, +1
Frontiers in Immunology
2022
28
423 Safety and preliminary efficacy of intratumoral cavrotolimod (AST-008), a spherical nucleic acid TLR9 agonist, in combination with pembrolizumab in patients with advanced solid tumors
Steven O’Day, Cesar A. Perez, Trisha M. Wise‐Draper, +21
Regular and Young Investigator Award Abstracts
ImmunologyImmunoeditingImmunotherapeuticsPreliminary EfficacySpherical 3D +21
2020
16
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