Lpath (United States)

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

Barbara Visentin, John Vekich, Bradley J. Sibbald et al. · Cancer Cell · 2006 · 449 citations · Full text

Anti-sphingosine-1-phosphate Antibody, Angiogenesis, Medicine +12

NRF2 Activation Promotes Aggressive Lung Cancer and Associates with Poor Clinical Outcomes

Anju Singh, Anneleen Daemen, Dorothee Nickles et al. · Clinical Cancer Research · 2020 · 168 citations · Full text

Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

Yapeng Gu, Tetyana V. Forostyan, Roger A. Sabbadini et al. · The Journal of Cell Biology · 2011 · 167 citations · Full text

Apoptosis, Cell Death, Cytoskeleton +17

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor- -stimulated collagen production by cardiac fibroblasts

Nicole Gellings Lowe, James S. Swaney, Kelli Moreno et al. · Cardiovascular Research · 2008 · 142 citations · Full text

Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1‐phosphate signalling to regulate tumour metastasis

Suriyan Ponnusamy, Shanmugam Panneer Selvam, Shikhar Mehrotra et al. · EMBO Molecular Medicine · 2012 · 140 citations · Full text