Molecular Partners (Switzerland)

Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors

Gaby Sennhauser, Patrick Amstutz, Christophe Briand et al. · PLoS Biology · 2006 · 325 citations · Full text

Efficient Tumor Targeting with High-Affinity Designed Ankyrin Repeat Proteins: Effects of Affinity and Molecular Size

Christian Zahnd, Martin Kawe, Michael T. Stumpp et al. · Cancer Research · 2010 · 245 citations

Immunology, Tumor Uptake, Cancer Biology +18

Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells

Alexander Eggel, Günther Baravalle, Gabriel Hobi et al. · Journal of Allergy and Clinical Immunology · 2014 · 147 citations · Full text

Ige-fcεri Complexes, Signal Transduction, Allergy +12

Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism

Andreas Schweizer, Heidi Roschitzki‐Voser, Patrick Amstutz et al. · Structure · 2007 · 130 citations · Full text

Protein Function, Signal Transduction, Inhibition Mechanism +11

Treatment of Diabetic Macular Edema With a Designed Ankyrin Repeat Protein That Binds Vascular Endothelial Growth Factor: A Phase I/II Study

Peter A. Campochiaro, Roomasa Channa, Brian B. Berger et al. · American Journal of Ophthalmology · 2012 · 110 citations

Diabetic Retinopathy, Ophthalmology, Phase I/ii Study +9