Allozyne (United States)

Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody–Drug Conjugates Using Click Cycloaddition Chemistry

Michael Pete VanBrunt, Kurt Shanebeck, Zachary Caldwell et al. · Bioconjugate Chemistry · 2015 · 137 citations

Medicinal Chemistry, Drug Targeting, Biochemistry +15

Processing of N‐Terminal Unnatural Amino Acids in Recombinant Human Interferon‐β in <i>Escherichia coli</i>

Aijun Wang, Natalie W. Nairn, Richard S. Johnson et al. · ChemBioChem · 2007 · 60 citations · Full text

Engineering, Amino Acids, Molecular Biology +18

Development of Copper-Catalyzed Azide–Alkyne Cycloaddition for Increased in Vivo Efficacy of Interferon β-1b by Site-Specific PEGylation

Natalie W. Nairn, Kurt Shanebeck, Aijun Wang et al. · Bioconjugate Chemistry · 2012 · 37 citations

Peg Size, Medicinal Chemistry, Biochemistry +14

AZ17: a new bispecific drug targeting IL-6 and IL-23 with potential clinical use—improves psoriasis in a human xenograft transplantation model

Karin Stenderup, Cecilia Rosada, Kurt Shanebeck et al. · Protein Engineering Design and Selection · 2015 · 16 citations · Full text

Human Il-6, Psoriasis Skin, Immunology +18