Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice

Osamu Ishida, Kazuo Maruyama, Katsunori Sasaki, +1

International Journal of Pharmaceutics

Cell-based Drug DeliveryNanomedicineEngineeringExtracellular MicrovesiclesVascular Biology +10

Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol) s conjugated at their distal terminals to monoclonal antibodies

Kazuo Maruyama, Tomoko Takizawa, Tsutomu Yuda, +3

Biochimica et Biophysica Acta (BBA) - Biomembranes

Ethylene GlycolDistal TerminalsPolymer-drug ConjugateGlycobiologyImmunology +8

Liposomes Bearing Polyethyleneglycol-Coupled Transferrin with Intracellular Targeting Property to the Solid Tumors In Vivo

Osamu Ishida, Kazuo Maruyama, Hiroyuki Tanahashi, +4

Pharmaceutical Research

Prolonged circulation time in vivo of large unilamellar liposomes composed of distearoyl phosphatidylcholine and cholesterol containing amphipathic poly(ethylene glycol)

Kazuo Maruyama, Tsutomu Yuda, Aki Okamoto, +3

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Ethylene GlycolEngineeringBiochemistryCirculation TimeLarge Unilamellar Liposomes +5

Immunoliposomes bearing polyethyleneglycol‐coupled Fab′ fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo

Kazuo Maruyama, Nobuya Takahashi, Toshiaki Tagawa, +2

FEBS Letters

Peg TerminalsEngineeringSolid TumorsImmunologySolid Tumor +16

Direct measurement of the extravasation of polyethyleneglycol-coated liposomes into solid tumor tissue by in vivo fluorescence microscopy

Sakae Unezaki, Kazuo Maruyama, Jun-Ichi Hosoda, +6

International Journal of Pharmaceutics

NanomedicineSolid Tumor TissueTissue ImagingEngineeringBiomedical Imaging +6

Enhanced delivery of doxorubicin to tumor by long-circulating thermosensitive liposomes and local hyperthermia

Kazuo Maruyama, Sakae Unezaki, Noriyuki Takahashi, +1

Biochimica et Biophysica Acta (BBA) - Biomembranes

Cell-based Drug DeliveryNanomedicineLong-circulating Thermosensitive LiposomesNanotherapeuticsLocal Hyperthermia +10

Enhanced Delivery and Antitumor Activity of Doxorubicin Using Long-Circulating Thermosensitive Liposomes Containing Amphipathic Polyethylene Glycol in Combination with Local Hyperthermia

Sakae Unezaki, Kazuo Maruyama, Noriyuki Takahashi, +4

Pharmaceutical Research

Targeting efficiency of PEG-immunoliposome-conjugated antibodies at PEG terminals

Kazuo Maruyama, Tomoko Takizawa, Nobuya Takahashi, +3

Advanced Drug Delivery Reviews

Peg TerminalsImmunoengineeringImmunologyAntibody ScreeningImmunochemistry +3

Preventive effects of pyrroloquinoline quinone on formation of cataract and decline of lenticular and hepatic glutathione of developing chick embryo after glucocorticoid treatment

Hideo Nishigori, Mika Yasunaga, Masashi Mizumura, +2

Life Sciences

OphthalmologyMedicinePyrroloquinoline QuinoneGlucocorticoid TreatmentGlucocorticoid +3