Lai Wang

Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL

Constantine S. Tam, Judith Trotman, Stephen Opat et al. · Blood · 2019 · 367 citations · Full text

Medicine, Oncology, Pharmacology +10

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Yunhang Guo, Ye Liu, Nan Hu et al. · Journal of Medicinal Chemistry · 2019 · 349 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Inhibition of Human Immunodeficiency Virus Type 1 Transcription by Chemical Cyclin-Dependent Kinase Inhibitors

Dai Wang, Cynthia de la Fuente, Longwen Deng et al. · Journal of Virology · 2001 · 133 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +10

The BTK Inhibitor, Bgb-3111, Is Safe, Tolerable, and Highly Active in Patients with Relapsed/ Refractory B-Cell Malignancies: Initial Report of a Phase 1 First-in-Human Trial

Constantine S. Tam, Andrew Grigg, Stephen Opat et al. · Blood · 2015 · 111 citations

Medicine, Hematology, Oncology +10

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death

Fatih Akdemir, Róbert Farkas, Po Chen et al. · Development · 2006 · 102 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17