Hypoxia promotes a dedifferentiated phenotype in ductal breast carcinoma in situ.

Karolina Helczynska, Åsa Kronblad, Annika Jögi, +4

PubMed

Breast OncologyPathologyCell DeathCell ProliferationCancer Biology +17

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

Jonas Sjölund, Martin Johansson, Sugata Manna, +6

Journal of Clinical Investigation

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

Katleen De Preter, Jo Vandesompele, Pierre Heimann, +11

Genome biology

HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

Alexander Pietras, Loen M. Hansford, A. Johnsson, +11

Proceedings of the National Academy of Sciences

High Hypoxia-inducible Factor-2alphaCancer BiologyGliomaNeuroblastoma CellsTumor Biology +15

Neuroblastoma patient‐derived orthotopic xenografts retain metastatic patterns and geno‐ and phenotypes of patient tumours

Noémie Braekeveldt, Caroline Wigerup, David Gisselsson, +12

International Journal of Cancer

HIF-2α expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia

Helén Nilsson, Annika Jögi, Siv Beckman, +3

Experimental Cell Research

Developmental BiologyMolecular NeuroscienceMedicinePhysiologyHypoxia (Medicine) +5

HIF-1α and HIF-2α Are Differentially Regulated <i>In vivo</i> in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization

Rosa Noguera, Erik Fredlund, Marta Piqueras, +4

Clinical Cancer Research

Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma

Noémie Braekeveldt, Kristoffer von Stedingk, Susanne Fransson, +19

Cancer Research

Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours

Noémie Braekeveldt, Caroline Wigerup, Irene Tadeo, +13

Cancer Letters

Tumor BiologyTumoral PathologyTumor InnervationGliomaMalignant Disease +13

Hypoxic Conditions Induce a Cancer-Like Phenotype in Human Breast Epithelial Cells

Marica Vaapil, Karolina Helczynska, René Villadsen, +6

PLoS ONE