Melika Rezaee

Smoothened Variants Explain the Majority of Drug Resistance in Basal Cell Carcinoma

Scott X. Atwood, Kavita Y. Sarin, Ramon J. Whitson et al. · Cancer Cell · 2015 · 415 citations · Full text

Oncology, Health Sciences, Somatic Variant +12

Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

James Kim, Blake T. Aftab, Jean Y. Tang et al. · Cancer Cell · 2013 · 329 citations · Full text

Smoothened Antagonists, Chemoprevention Strategy, Acquired Resistance +8

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Christopher J. Nirschl, Mayte Suárez‐Fariñas, Benjamin Izar et al. · Cell · 2017 · 188 citations · Full text

Ifnγ-dependent Tissue-immune Homeostasis, Cancer Immunosurveillance, Immunology +6

Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Jean Y. Tang, Mina S. Ally, Anita M. Chanana et al. · The Lancet Oncology · 2016 · 134 citations

Medicine, Basal-cell Nevus Syndrome, Clinical Trials +10

Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma

Mina S. Ally, Katherine J. Ransohoff, Kavita Y. Sarin et al. · JAMA Dermatology · 2016 · 89 citations · Full text