Elizabeth Smoot Malecha

Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study

Michael Trauner, Frederik Nevens, Mitchell L. Shiffman et al. · ˜The œLancet. Gastroenterology & hepatology · 2019 · 176 citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +12

Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls

Carla Fiorella Murillo Perez, Holly Fisher, Shaun Hiu et al. · Gastroenterology · 2022 · 101 citations · Full text

Medicine, Internal Medicine, Surgery +17

COBALT: A Confirmatory Trial of Obeticholic Acid in Primary Biliary Cholangitis With Placebo and External Controls

Kris V. Kowdley, Gideon M. Hirschfield, Charles Coombs et al. · The American Journal of Gastroenterology · 2024 · 60 citations · Full text

Medicine, Internal Medicine, Pharmacotherapy +9

Reduction and stabilization of bilirubin with obeticholic acid treatment in patients with primary biliary cholangitis

Albert Parés, Mitchell L. Shiffman, Vı́ctor Vargas et al. · Liver International · 2020 · 19 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +14

Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis

Maren H. Harms, Gideon M. Hirschfield, Annarosa Floreani et al. · JHEP Reports · 2020 · 16 citations · Full text

Medicine, Pharmacotherapy, Hepatic Pharmacokinetics +16