James Empfield

Molecular Pharmacology of Selective Na _V 1.6 and Dual Na _V 1.6/Na _V 1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo

Samuel J. Goodchild, Noah Gregory Shuart, Aaron D. Williams et al. · ACS Chemical Neuroscience · 2024 · 26 citations · Full text

Medicine, Neuroscience, Pharmacology +17

K-Channel Opening Activity of ZD6169 and Its Analogs: Effect on ⁸⁶ Rb Efflux and ³ H-P1075 Binding in Bladder Smooth Muscle

S.L. Stetz, L. Potter-Lee, Malcolm J. McConville et al. · Pharmacology · 2008 · 24 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1

Michael J. Boyd, Philip N. Collier, Michael P. Clark et al. · Journal of Medicinal Chemistry · 2021 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Pyridazinoquinolinetriones as NMDA Glycine-Site Antagonists with Oral Antinociceptive Activity in a Model of Neuropathic Pain

Thomas M. Bare, Dean G. Brown, Carey L. Horchler et al. · Journal of Medicinal Chemistry · 2007 · 15 citations

Medicine, Neuroscience, Pharmacology +17