Human Toll‐Like Receptor 4 Mutations but Not CD14 Polymorphisms Are Associated with an Increased Risk of Gram‐Negative Infections

Doreen M. Agnese, Jacqueline E. Calvano, Sae J. Hahm, +4

The Journal of Infectious Diseases

Microbial PathogensInnate Immune SystemImmunologyInnate ImmunityImmune-related Gene Polymorphism +15

Cytokine appearance in human endotoxemia and primate bacteremia.

David G. Hesse, Kevin J. Tracey, Yuman Fong, +5

PubMed

InflammationCytokineMicrobial PathogensBacterial InfusionLive Escherichia Coli +9

IL-8 in septic shock, endotoxemia, and after IL-1 administration

Kimberly J. Van Zee, Laura DeForge, E Fischer, +5

The Journal of Immunology

The biologic characteristics of cytokines and their implication in surgical injury.

Yuman Fong, Lyle L. Moldawer, G. Tom Shires, +1

PubMed

ImmunologyPathologyCell DeathSurgeryModerate Quantities +17

Interleukin 1 receptor blockade attenuates the host inflammatory response.

Jeffrey E. Gershenwald, Yuman Fong, Thomas J. Fahey, +5

Proceedings of the National Academy of Sciences

Passive ImmunizationImmunologyImmune RegulationPathologyImmunologic Mechanism +14

Passive immunization against tumor necrosis factor-alpha impairs host defense during pneumococcal pneumonia in mice.

Tom van der Poll, C V Keogh, Wim A. Buurman, +1

American Journal of Respiratory and Critical Care Medicine

InflammationCytokineHost ResponseLung Tnf ActivityLung Inflammation +13

The role of cytokine mediators in septic shock.

Kevin J. Tracey, S F Lowry

PubMed

Acute Lung InjuryInflammationCytokineImmunologyCytokine Mediators +5

Mobilization of potent plasma bactericidal activity during systemic bacterial challenge. Role of group IIA phospholipase A2.

Yvette Weinrauch, Concepción Abad, Ning S. Liang, +2

Journal of Clinical Investigation

Microbial PathogensBactericidal ActivityImmunologyEscherichia ColiBacterial Pathogens +20

Effects of intravenous IL-8 administration in nonhuman primates

Kimberly J. Van Zee, E Fischer, A S Hawes, +5

The Journal of Immunology

Interleukin-1 alpha and tumor necrosis factor alpha cause placental injury in the rat.

Mark L. Silen, Adolfo Firpo, Susan Morgello, +2

PubMed