Jin Suo

Design, Synthesis, and Pharmacological Evaluation of Monocyclic Pyrimidinones as Novel Inhibitors of PDE5

Guan Wang, Zheng Liu, Tiantian Chen et al. · Journal of Medicinal Chemistry · 2012 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pharmacokinetics-Driven Optimization of 4(3<i>H</i>)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension

Zhen Wang, Xiangrui Jiang, Xianglei Zhang et al. · Journal of Medicinal Chemistry · 2019 · 37 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +14

A practical and enantioselective synthesis of tapentadol

Qıang Zhang, Jianfeng Li, Tian Guang-hui et al. · Tetrahedron Asymmetry · 2012 · 17 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

Oxidative Aromatization of 3,4-Dihydroquinolin-2(1<i>H</i>)-ones to Quinolin-2(1<i>H</i>)-ones Using Transition-Metal-Activated Persulfate Salts

Weiming Chen, Chang‐Liang Sun, Yan Zhang et al. · The Journal of Organic Chemistry · 2019 · 17 citations

Natural Sciences, Chemistry, Green Chemistry +6

Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety

Wenjiao Yang, Xudong Gong, Haiguo Sun et al. · European Journal of Medicinal Chemistry · 2023 · 16 citations

Medicine, Medicinal Chemistry, Pharmacology +12