Wenxian Lu

Pin1 inhibition reverses the acquired resistance of human hepatocellular carcinoma cells to Regorafenib via the Gli1/Snail/E-cadherin pathway

Jichuang Wang, Nan Zhang, Qi Han et al. · Cancer Letters · 2018 · 105 citations

Pin1 Inhibition, Signaling Pathway, Acquired Resistance +8

A novel controlled release formulation of the Pin1 inhibitor ATRA to improve liver cancer therapy by simultaneously blocking multiple cancer pathways

Dayun Yang, Wensong Luo, Jichuang Wang et al. · Journal of Controlled Release · 2017 · 71 citations · Full text

Chemoprevention Strategy, Medicine, Release Formulation +9

Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways

Xin-Hua Liao, Arina Li Zhang, Min Zheng et al. · Scientific Reports · 2017 · 51 citations · Full text

Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma

Min Zheng, Huijuan Xu, Xin‐Hua Liao et al. · Oncotarget · 2017 · 37 citations · Full text

Tumor Biology, Inhibit Tumor Growth, Hepatology +15

Pin1 inhibition potently suppresses gastric cancer growth and blocks PI3K/AKT and Wnt/β‐catenin oncogenic pathways

Zhenzhen Zhang, Weixing Yu, Min Zheng et al. · Molecular Carcinogenesis · 2019 · 33 citations · Full text

Tumor Biology, Pin1 Inhibition, Gastrointestinal Oncology +14