E. Rand Sutherland

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial

Sally E. Wenzel, Mario Castro, Jonathan Corren et al. · The Lancet · 2016 · 880 citations

Medicine, Internal Medicine, Pharmacology +13

Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis

Claus Bachert, Leda Mannent, Robert M. Naclerio et al. · JAMA · 2016 · 785 citations · Full text

Medicine, Immunology, Otolaryngology +14

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

Yvonne J. Huang, Craig E. Nelson, Eoin Brodie et al. · Journal of Allergy and Clinical Immunology · 2010 · 696 citations · Full text

Life Sciences, Immunology, Microbiology +14

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

Diamant Thaçi, Eric L. Simpson, Lisa A. Beck et al. · The Lancet · 2015 · 566 citations

Life Sciences, Dermatology, Immunology +11

Tiotropium Bromide Step-Up Therapy for Adults with Uncontrolled Asthma

Stephen P. Peters, Susan J. Kunselman, Nikolina Icitovic et al. · New England Journal of Medicine · 2010 · 512 citations · Full text

Pharmacy, Internal Medicine, Pharmacotherapy +14