Jun-ichi Furuyama

Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy.

Reigetsu Yoshikawa, M. Kusunoki, Hidenori Yanagi et al. · PubMed · 2001 · 194 citations

Oncology, Medicine, Metronomic Therapy +15

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population

Tatsuya Takeshita, Kanehisa Morimoto, XiaoQuang Mao et al. · Human Genetics · 1994 · 165 citations

Biology, Japanese Population, Aldehyde Dehydrogenase +8

Association between genetic variants of mast-cell chymase and eczema

X.‐Q. Mao, Taro Shirakawa, Tsutomu Yoshikawa et al. · The Lancet · 1996 · 161 citations

Genetic Variants, Autoimmune Disease, Atopic Dermatitis +7

Inactivation of the cholinesterase gene by Alu insertion: possible mechanism for human gene transposition.

Kazuki Muratani, Tomonori Hada, Yoshihiro Yamamoto et al. · Proceedings of the National Academy of Sciences · 1991 · 157 citations · Full text

Che Gene, Genetic Disorder, Natural Sciences +14

Polymorphisms of the TNF gene and the TNF receptor superfamily member 1B gene are associated with susceptibility to ulcerative colitis and Crohn's disease, respectively

Hiroko Sashio, Kazuo Tamura, Reiko Ito et al. · Immunogenetics · 2002 · 153 citations

Inflammation, Genetic Epidemiology, Immunology +9